GLP-1 Medication Reviews
In-depth reviews of the most popular GLP-1 medications for weight management and type 2 diabetes — grouped by drug class so you can compare your options.
Semaglutide
GLP-1 receptor agonist by Novo Nordisk
Ozempic
The original weekly semaglutide injection. FDA-approved for type 2 diabetes and cardiovascular risk reduction, widely used off-label for weight loss.
Manufacturer: Novo Nordisk
Form: Weekly injection
Approved for: Type 2 diabetes
Wegovy
Higher-dose semaglutide specifically approved for chronic weight management. Clinical trials showed up to 15% average body weight reduction.
Manufacturer: Novo Nordisk
Form: Weekly injection
Approved for: Weight management
Rybelsus
The first oral GLP-1 medication. Offers the convenience of a daily pill instead of injections — an important option for needle-averse patients.
Manufacturer: Novo Nordisk
Form: Daily oral tablet
Approved for: Type 2 diabetes
Tirzepatide
Dual GIP/GLP-1 receptor agonist by Eli Lilly
Mounjaro
The first dual GIP/GLP-1 receptor agonist. Approved for type 2 diabetes and showing the highest weight loss results of any GLP-1 class drug in trials.
Manufacturer: Eli Lilly
Form: Weekly injection
Approved for: Type 2 diabetes
Zepbound
Tirzepatide approved for weight management and obstructive sleep apnea. Trials showed average weight loss of 20–22% — the highest of any approved medication.
Manufacturer: Eli Lilly
Form: Weekly injection
Approved for: Weight management & sleep apnea
Liraglutide
Daily GLP-1 receptor agonist by Novo Nordisk
Saxenda
The first GLP-1 medication approved specifically for weight management. Requires a daily injection but has a long safety track record since its 2014 approval.
Manufacturer: Novo Nordisk
Form: Daily injection
Approved for: Weight management
Victoza
Daily liraglutide approved for type 2 diabetes management and cardiovascular risk reduction. One of the earliest GLP-1 medications with extensive real-world data.
Manufacturer: Novo Nordisk
Form: Daily injection
Approved for: Type 2 diabetes
Dulaglutide
Weekly GLP-1 receptor agonist by Eli Lilly
Helpful Guides & Articles
Ozempic vs. Wegovy: Which Is Right for You?
Both are semaglutide — here's how to decide which fits your goals.
Read guideSemaglutide vs. Tirzepatide: Comparing GLP-1 Types
The key clinical differences between the two leading GLP-1 drug classes.
Read guideGLP-1 Medication Costs Without Insurance
Real list prices and all the ways to reduce what you pay out of pocket.
Read articleNeed Help Choosing?
Selecting the right GLP-1 medication depends on your individual health needs, lifestyle, and goals. Consult with a licensed healthcare provider to determine which option is best for you.
Contact Us